ABSTRACT The critical virulence factor of bloodstream-form Trypanosoma brucei is the glycosylphosphatidylinositol (GPI)-anchored variant surface glycoprotein (VSG). Endoplasmic reticulum (ER) exit of VSG is GPI dependent and relies on a discrete subset of COPII machinery (TbSec23. 2/TbSec24. https://safeersappliancers.shop/product-category/bosch-dhl785cgb-serie-6-built-in-70cm-4-speeds-c-rated-canopy-cooker-hood/