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Functional Analysis of Variants in Complement Factor I Identified in Age-Related Macular Degeneration and Atypical Hemolytic Uremic Syndrome

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Complement factor I (FI) is a central inhibitor of the complement system. and impaired FI function increases complement activation. contributing to diseases such as age-related macular degeneration (AMD) and atypical hemolytic uremic syndrome (aHUS). Genetic variation in complement factor I (CFI) has been identified in both AMD and aHUS. https://quarterfoures.shop/product-category/mens/
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