Background: Irritable bowel syndrome (IBS) is characterized by abdominal pain and altered bowel habits. Further. IBS patients experience a high degree of extraintestinal symptoms. Objectives: The aim of this review was to describe the relation between IBS and extraintestinal manifestations and mechanisms and treatments of these extraintestinal manifestations. https://www.roneverhart.com/Echo-Fix-EF-P2-Spring-Reverb-Pedal-p32083/