The prevalence of HIV-associated neurocognitive disorders (HAND) remains high despite effective antiretroviral therapies. Multiple etiologies have been proposed over the last several years to account for this phenomenon. including the neurotoxic effects of antiretrovirals and co-morbid substance abuse; however. no underlying molecular mechanism has been identified. https://www.alarecre.com/Looney-Tunes-Marvin-the-Martian-Big-Head-Galaxy-S23-Waterproof-Case-p116784/